Biologist

<section style="font-size: 10.0pt; font-family: 'Tahoma',sans-serif;"> <div> <p><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">(ID: 2026-3795)</span></p> <br> <p><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Axle</strong> is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).</span></p> </div> <br> <div> <p><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Axle</strong> is seeking a <strong><em>Biologist </em></strong> to join our vibrant team at the National Institutes of Health (NIH) supporting the <strong>National Heart, Lung, and Blood Institute (NHLBI) located in Bethesda, MD.</strong></span></p> </div> <br> <div> <p><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Benefits We Offer:</strong></span></p> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">100% Medical, Dental &amp; Vision Coverage for Employees</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Paid Time Off and Paid Holidays</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">401K match up to 5%</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Educational Benefits for Career Growth</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Employee Referral Bonus</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Flexible Spending Accounts:</span> <ul> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Healthcare (FSA)</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Parking Reimbursement Account (PRK)</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Dependent Care Assistant Program (DCAP)</span></li> <li style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><span style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">Transportation Reimbursement Account (TRN)</span></li> </ul> </li> </ul> </div> <div class="ck-content" style="font-family: Segoe UI; font-size: 11pt;" data-wrapper="true"> <p style="line-height: 105%; margin: 7.0pt 0in 4pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Position Overview</strong></span></p> <p style="line-height: 105%; margin: 0in 0in 4pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">The Biologist will support research on sleep and circadian behavior in Drosophila melanogaster. The role includes conducting multigeneration selective breeding experiments to develop flies with extreme sleep and circadian phenotypes, computing phenotypes from fly activity data, and performing statistical and quantitative genetics analyses. Additional responsibilities include molecular biology experiments, sequencing sample preparation and analysis, laboratory maintenance, staff training, and contributions to scientific publications.</span></p> <p style="line-height: 105%; margin: 7.0pt 0in 4pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Additional Qualifications</strong></span></p> <p style="line-height: 105%; margin: 7.0pt 0in 4pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Education</strong></span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Ph.D. in a scientific field. A master's degree plus three years of specialized experience, or a bachelor's degree plus five years of specialized experience, may substitute for the Ph.D.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Fields of study: Genetics, Microbiology, or Chemistry.</span></p> <p style="line-height: 105%; margin: 7.0pt 0in 4pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Experience and Skills</strong></span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• General experience with basic biochemical and molecular biology techniques and an understanding of general scientific principles.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Proficiency in selective breeding of Drosophila melanogaster.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Proficiency in measuring sleep and circadian behavior in flies and computing sleep and circadian phenotypes from raw activity data.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Proficiency in conducting statistical analyses of sleep and circadian behavior.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Self-motivation, attention to detail, and strong organizational skills.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Strong oral and written communication skills.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Excellent analytical and time-management skills.</span></p> <p style="line-height: 105%; margin: 7.0pt 0in 4pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Software</strong></span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Microsoft Suite</span></p> <p style="line-height: 105%; margin: 7.0pt 0in 4pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Deliverables</strong></span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Inspect equipment&nbsp;</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Produce work products and documentation related to selective breeding of flies for extreme sleep and circadian phenotypes&nbsp;</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Produce work products and documentation related to computing sleep phenotypes and conducting statistical and quantitative genetics analyses</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Produce work products and documentation related to preparing fly samples for deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) sequencing, reverse transcription quantitative polymerase chain reaction (RT-qPCR) experiments, and sequencing data analysis&nbsp;</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Maintain accurate experimental records, participate in laboratory meetings and planning sessions, and contribute to scientific papers for publication&nbsp;</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Prepare samples for research assays, assist in processing patient samples, and train summer students and research fellows in basic fly culturing and molecular biology techniques&nbsp;</span></p> <p style="line-height: 105%; margin: 7.0pt 0in 4pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;"><strong>Statement of Work Details</strong></span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Conduct multigeneration selective breeding experiments to develop flies with extreme sleep and circadian phenotypes.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Compute sleep and circadian phenotypes from fly activity data.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Conduct statistical analyses of sleep and circadian behavior, including quantitative genetics analyses.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Maintain Drosophila cultures for experimental purposes.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Perform Sanger sequencing analysis of genomic DNA samples obtained from Drosophila.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Prepare DNA and RNA samples for next-generation sequencing.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Conduct confirmatory experiments using RT-qPCR.</span></p> <p style="line-height: 105%; margin: 0in 0in 4pt 9.35pt;"><span style="color: black; font-family: tahoma, arial, helvetica, sans-serif; font-size: 10pt;">• Prepare samples for laboratory team members' research assays and prov